Fc-optimized anti-CTLA-4 antibodies increase tumor-associated high endothelial venules and sensitize refractory tumors to PD-1 blockade.

Cell Rep Med · 2025 · PMC12208319 · PMID 40460830

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hedged sentence

0.0666

closest p · 1.3× alpha

0.0666

boldest claim

The sentences

almost significantlyp = 0.0666so close (0.05 < p ≤ 0.1)

The number of MECA-79 − TA-ECs was reduced ( Figure S10 C) but not the number of MECA-79 + TA-HECs that was almost significantly increased ( p = 0.0666, Figure S10 D).

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