Insulin- and exercise-induced phosphoproteomics of human skeletal muscle identify REPS1 as a regulator of muscle glucose uptake.

To gain further insights into their upstream kinases, we conducted a motif enrichment analysis, revealing a prevalent sequence motif surrounding the phosphosites with a highly significant proportion of arginine at position −3 (odds ratio = 4, p = 5e−05) ( Figure 2 G).

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