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Diversity of mast cell subpopulations in the tumor microenvironment of colorectal cancer and their prognostic implications.

Cancer Immunol Immunother · 2025 · PMC12209079 · PMID 40586903

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Additionally, CytoTrace analysis was used to evaluate the differentiation potential of different mast cell subpopulations, with results showing a decreasing trend in CytoTrace scores across the three subpopulations, indicating that Mast Cell 1 may differentiate into Mast Cell 2 and Mast Cell 3 (Fig. 3 G).

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