Barely Significant
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Global burden of early-onset gallbladder and biliary tract cancer from 1990 to 2021.

BMC Gastroenterol · 2025 · PMC12210556 · PMID 40597693

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an increasing trendno p-value reported
The study identified an increasing trend in the numbers of prevalence and incidence across the majority of SDI regions.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.