Low-dose radiotherapy enhances the efficacy of PD-L1 blockade and induces the abscopal effect.

J Immunother Cancer · 2025 · PMC12211843 · PMID 40588370

Europe PMC DOI

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a positive trendp=0.08so close (0.05 < p ≤ 0.1)

Furthermore, the combination of low-dose RT 2×2 Gy to primary tumors with anti-PD-L1 showed a positive trend in the growth of secondary tumors compared with anti-PD-L1 alone ((2×2 Gy+anti-PD-L1) vs (NIR+anti-PD-L1): p=0.08).

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