Barely Significant
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Efficacy and Safety of Higher Doses of Levofloxacin for Multidrug-resistant Tuberculosis: A Randomized, Placebo-controlled Phase II Clinical Trial.

Am J Respir Crit Care Med · 2025 · PMC12213226 · PMID 40080768

1
hedged sentence
0.0420
closest p · 0.8× alpha
0.0420
boldest claim

The sentences

an increasing trendP = 0.042actually significant
By the Cochrane-Armitage test, there was evidence of an increasing trend in the proportion of participants experiencing a grade 3–5 AE ( P = 0.042) by tertile of AUC ( P = 0.022) and in the proportion of participants experiencing any SAE by tertile of AUC ( P = 0.011; Tables 2 and 3 ).

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