Data simulation to optimize frameworks for genome-wide association studies in diverse populations.

Front Genet · 2025 · PMC12213643 · PMID 40606669

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marginal significanceno p-value reported

In comparison, in the African simulated GWAS dataset with the smaller sample size, we observed that all the tools, except for SNPTEST, were only able to capture the signals on chromosomes 2, 6, and 20 at significant levels and the signals on chromosomes 15 only at marginal significance thresholds.

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