Divergent trajectories to structural diversity impact patient survival in high grade serous ovarian cancer.

Nat Commun · 2025 · PMC12215056 · PMID 40593568

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failed to reach significanceno p-value reported

Supporting this, we found that significantly lower expression of PTEN (a known tumour suppressor gene (TSG) in HGSOC) was associated with CNA deletion, but as this was seen in only one sub-cohort, it failed to reach significance (FDR < 0.05) and was excluded.

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