used databases and machine learning approaches to report that CK23 plays a major role in metastasis and has highly significant results in survival analyses. 229 A retrospective study using microarray datasets of bone metastases and metastasis-free breast cancer patients revealed that CK23 is a gene associated with bone metastases through bioinformatics analysis.
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Cytokeratin expression in breast cancer: from mechanisms, progression, diagnosis, and prognosis to therapeutic implications.
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