Tumor suppressors in Sox2-mediated lung cancers promote distinct cell-intrinsic and immunologic remodeling.

JCI Insight · 2025 · PMC12220946 · PMID 40327401

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highly significantno p-value reported

Differential expression analysis of TIMs from LN2A model compared with the SNL models revealed highly significant increases of leucine-rich α-2 glycoprotein 1 ( Lrg1 ) and interleukin-1 receptor type 2 ( Il-1r2 ) upregulation in addition to CD38 ( Figure 5G ).

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