Secular Trends in the Prevalence of Total and Latent Prostate Cancer over Half a Century According to Consecutive Autopsy Cases in a Japanese community: The Hisayama Study.

Eur Urol Open Sci · 2025 · PMC12221362 · PMID 40606513

Europe PMC DOI

hedged sentences

0.0520

closest p · 1.0× alpha

0.0520

boldest claim

The sentences

marginally significantp = 0.052so close (0.05 < p ≤ 0.1)

For the group aged ≥80 yr at death, the increase in the CPP of LPC from 4.8% (95% CI 0–10%) in 1962–1976 to 15% (95% CI 9.7–20%) in 2007–2020) was marginally significant ( p = 0.052).

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an increasing trendno p-value reported

Since our analysis for consecutive autopsy cases in a community revealed an increasing trend in the period prevalence of PC in subgroup analyses adjusted for age at death, the recent increase in PC prevalence is likely to involve additional factors beyond improvements in screening and diagnostic techniques and the aging of the population.

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