Barely Significant
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Enhanced trafficking of an inherited erythromelalgia Na<sub>V</sub>1.7 mutant channel at a physiological temperature.

Neurobiol Pain · 2025 · PMC12221430 · PMID 40606587

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highly significantp < 0.0001actually significant
2 C ), the mutant main-effect on channel activation was highly significant ( p < 0.0001, two-way ANOVA), confirming the expected hyper-polarizing shift produced by L858F.

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