Clinical TP53 genetic testing is recommended for HER2-positive breast cancer patients aged 35 or younger.

NPJ Genom Med · 2025 · PMC12223164 · PMID 40603321

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an increasing trendno p-value reported

Early-onset breast cancer, defined as breast cancer diagnosed at age of 40 years or younger, accounts for >16% of cases, with an increasing trend in China 1 , 2 .

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