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Extracellular vesicle-derived miR-146a as a novel crosstalk mechanism for high-fat induced atherosclerosis by targeting SMAD4.

J Adv Res · 2025 · PMC12225892 · PMID 39127099

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noticeably significantno p-value reported
6 D) while fat enriched diet group with miR-146a-5p inhibitor showed noticeably significant inhibition of atherosclerosis associated plaque development in comparison to standard (negative) control fat rich diet group ( Fig. 6 C-E) indicating the clear involvement of miR-146a-5p in the development of plaque.

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