Precision-edited histone tails disrupt polycistronic gene expression controls in trypanosomes.

Nat Commun · 2025 · PMC12227686 · PMID 40615444

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highly significantno p-value reported

H4 ECT gene recoding meant that we could readily distinguish between native H4 and H4 ECT expression and indeed, the transcriptomes revealed highly significant changes in the expression of these two genes.

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