Multiparametric quantitative MRI uncovers putamen microstructural changes in Parkinson's disease.

NPJ Parkinsons Dis · 2025 · PMC12229524 · PMID 40610525

Europe PMC DOI

hedged sentences

0.0000

closest p · 0.0× alpha

0.0300

boldest claim

The sentences

highly significantP < 10 −10actually significant

Relatively large and highly significant interaction effects were found in the gradients of WF ( β PD = 0.46, 95% CI = [0.33, 0.59], P < 10 −10 ) and R2* ( β PD = -0.47, 95% CI = [−0.63, -0.32], P < 10 −7 ).

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marginally significantP = 0.03actually significant

In R2*, we found marginally significant main effects of Age ( β = 0.19, 95% CI = [0.02, 0.36], uncorrected- P = 0.03), and Sex ( β male = −0.41, 95% CI = [−0.76, −0.05], uncorrected- P = 0.025).

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