Hypomethylating therapy mitigates acute allograft rejection in a murine lung transplant model.

Front Transplant · 2025 · PMC12230056 · PMID 40626170

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an overall trendno p-value reported

3.9 DAC-treatment of hosts shifts allograft CD8+ T cells toward an anti-inflammatory phenotype Having observed an overall trend towards the promotion of anti-inflammatory markers on live CD8+ T cells in allografts of DAC-treated hosts, we queried whether DAC administration to the host affected the relative magnitude of specific combinations of immunosuppressive markers characteristic of immunosuppressive CD8-phenotype populations.

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