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Club cell-derived brain-derived neurotrophic factor regulates murine airway mechanics and mucin production in response to IL-13 in a sex-dependent manner.

Front Physiol · 2025 · PMC12230438 · PMID 40626045

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a statistical trendno p-value reported
Our analysis of airway mechanics in mice revealed that reducing club cell Bdnf through conditional knockout had no major impacts on IL-13-mediated AHR, although a statistical trend for loss Bdnf to mitigate AHR was noted in female mice.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.