Barely Significant
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Global pattern, trend, and cross-country health inequality of adult acne aged 25 + years from 1990 to 2021, a comprehensive analysis for global burden of disease and global dietary database.

J Health Popul Nutr · 2025 · PMC12232192 · PMID 40616140

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a decreasing trendno p-value reported
Although the overall ASIR, age-standardized prevalence rate (ASPR), and age-standardized DALYs rate (ASDR) for adult acne globally have shown a decreasing trend since 1998/1999 (Fig. 1 D, E , F , Table 1 ).

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an increasing trendno p-value reported
In the stratification by SDI quintiles and GBD regions, the ASRs of adult acne showed an increasing trend in areas with low SDI, low-middle SDI, as well as regions like Western Sub-Saharan Africa and Eastern Sub-Saharan Africa.

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may be significantno p-value reported
Therefore, reducing the proportion of sugary beverages in the diet and improving dietary structure may be significant measures to alleviate the global burden of adult acne and narrow health disparities worldwide.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.