Hypoferremic Response to Chronic Inflammation Is Controlled via the Hemojuvelin/Hepcidin/Ferroportin Axis and Does Not Involve Hepcidin-Independent Regulation of Fpn mRNA.

Am J Hematol · 2025 · PMC12233014 · PMID 40347094

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an apparent trendno p-value reported

Immunohistochemical analysis in liver and spleen sections shows an apparent trend for a slight decrease in the intensity of ferroportin staining in Kupffer cells (Figure 3F ) and splenic macrophages (Figure 3I ), mainly in wild type mice with CKD.

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