Barely Significant
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Detection rate for ESR1 mutations is higher in circulating-tumor-cell-derived genomic DNA than in paired plasma cell-free DNA samples as revealed by ddPCR.

Mol Oncol · 2025 · PMC12234389 · PMID 39754401

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an obvious trendno p-value reported
One limitation of this study is the small sample size; we believe that this is the main reason that this difference in percentages is not clearly statistically significant but there is an obvious trend.

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