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Altered cortical thickness associated with psychotic symptoms and cognitive profiles in involuntarily hospitalized, first-episode, drug-naive patients with schizophrenia.

Front Psychiatry · 2025 · PMC12234461 · PMID 40630756

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a decreasing trendno p-value reported
The majority of studies indicate that patients with chronic schizophrenia typically exhibit a decreasing trend in cortical thickness, which is often associated with more severe cognitive impairments ( 26 – 29 ).

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