Single-cell transcriptome analysis reveals the malignant characteristics of tumour cells and the immunosuppressive landscape in HER2-positive inflammatory breast cancer.

First, we compared the number of interactions between the various cell types and found that there was a general trend towards enhanced interactions in IBC tumours, with only epithelial and endothelial cells showing a decreasing trend in the number of interactions, whereas mesenchymal and myeloid cells had the most numerous and complex network of interactions (Fig. 5 a).

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