The NPRS scale demonstrated an increasing trend across the grades of herniation, with median values rising from 4.00 in Grade 1, to 5.00 in Grade 2, and reaching 7.00 in Grade 3, with statistically significant differences [ P < 0.001; Table 1 ].
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High mobility group box 1 as a biomarker for lumbar disc herniation severity in chronic low back pain.
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