Global, regional, and national burden of chronic respiratory diseases,1990-2021 and predictions to 2035: analysis of data from the global burden of disease study 2021.

Conversely, a decreasing trend is observed when both the estimated EAPC and the upper limit of its 95% CI are below 0.

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In age-specific analyses of risk factors for CRD mortality, a notable trend was observed in high BMI, which increased rapidly among adults aged 20–24 years (10.36%) and peaked at age 45–49 years (18.15%), subsequently declining to 11.76% at age 80–84 years before rising again.

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The EAPC analysis demonstrated an increasing trend in ASDR for ILD and pulmonary sarcoidosis [EAPC = 0.95 (95% CI: 0.85–1.05)], while asthma [EAPC = −1.91(95% CI: −1.98, −1.83)], COPD [EAPC = −1.71 (95% CI: −1.79 to −1.63)], pneumoconiosis [EAPC = −2.63 (95% CI: −2.69 to −2.57)], and other CRDs [EAPC = −1.47 (95% CI: −1.60 to −1.34)] exhibited declining ASDR trends.

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