Naltrexone dose-selectively modulates goal-directed behavior and the hypothalamic proteome in rats.

Pharmacol Rep · 2025 · PMC12241218 · PMID 40434617

Europe PMC DOI

hedged sentence

0.0570

closest p · 1.1× alpha

0.0570

boldest claim

The sentences

marginally significantp = 0.057so close (0.05 < p ≤ 0.1)

Model (session x treatment) yielded that in PR, the mean number of lever presses differed across sessions ( χ 2 = 50.295, df = 6, p < 0.0001), and marginal effects indicated a significant reduction on the 4 th session (p = 0.001) and marginally significant reduction on 2 nd session (p = 0.057), as compared to the first test.

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