Aromatic scaffold-integrated hybrids of estradiol and benzoxazol-2-ones: synthesis and <i>in vitro</i> anticancer activity of <i>N</i>-substituted regioisomeric pairs.

RSC Adv · 2025 · PMC12242395 · PMID 40642461

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may not be significantno p-value reported

However, since the calculation method does not quantify the extent of permeation, the amount entering may not be significant enough to have a pronounced toxic effect.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Aromatic scaffold-integrated hybrids of estradiol and benzoxazol-2-ones: synthesis and &lt;i&gt;in vitro&lt;/i&gt; anticancer activity of &lt;i&gt;N&lt;/i&gt;-substituted regioisomeric pairs.

The sentences

Aromatic scaffold-integrated hybrids of estradiol and benzoxazol-2-ones: synthesis and <i>in vitro</i> anticancer activity of <i>N</i>-substituted regioisomeric pairs.