Discussion Due to changes in diet and lifestyle, metabolic diseases such as gout and HUA caused by purine metabolism disorders have shown an increasing trend worldwide [ 39 ].
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Interpretive prediction of hyperuricemia and gout patients via machine learning analysis of human gut microbiome.
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Our study found that both HUA and gout patients exhibited differences in gut microbiome composition compared to the healthy group, with a decreasing trend in microbial diversity (Fig. 3 A).