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Musculoskeletal organoids-on-chip uncover muscle-bone communication under intermittent hypoxia.

Natl Sci Rev · 2025 · PMC12243851 · PMID 40642332

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Chronic IH resulted in muscle injury, increasing the number of centralized nuclei in the gastrocnemius muscle of the hindlimb in HE staining, while a decreasing trend was observed after nanomedicine treatment ( Fig.

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