Barely Significant
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Clinical burden of pneumococcal disease among adults in France: A retrospective cohort study.

Hum Vaccin Immunother · 2025 · PMC12243894 · PMID 40633023

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an increasing trendno p-value reported
However, since 2015, there has been an increasing trend in IPD cases among all ages, including children ≤2 years of age and adults ≥65 years of age. 12 Mortality associated with IPD is estimated at 10–30%, depending on the study, and increases with age and presence of risk factors. 13 In France, S. pneumoniae is the leading cause of community-acquired b

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