Impaired Autophagic Flux in Skeletal Muscle of Plectin-Related Epidermolysis Bullosa Simplex With Muscular Dystrophy.

J Cachexia Sarcopenia Muscle · 2025 · PMC12246382 · PMID 40641151

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an overall trendno p-value reported

In keeping with this finding, evaluation of BAG3, SQSTM1, Ser403 phosphorylated SQSTM1, LC3‐I and LC3‐II revealed an overall trend towards increased autophagy marker proteins in CQ‐treated versus saline‐treated wild‐type muscles, while CQ‐treated MCK‐Cre/cKO muscles remained comparable to saline‐treated controls (Figure S8B;C ).

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