Barely Significant
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Effects of dapagliflozin on urinary output, fluid balance, and biochemistry in critically ill patients: a post-hoc secondary analysis of the DEFENDER trial.

Crit Care · 2025 · PMC12247443 · PMID 40646628

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a slight trendno p-value reported
The effect showed a slight trend from higher values in the dapagliflozin group on day 1 (0.09 mg/dL) to lower values by day 5 (−0.05), but with probabilities of direction that did not strongly support either direction (ranging from 0.39 to 0.73).

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