In many high-income countries, improved hygiene and living conditions have reduced the prevalence of oral infections during childhood [ 3 , 8 , 16–19 ], contributing to an increasing trend in the sexual acquisition of HSV-1 [ 8 , 20–23 ].
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Age-Dependent Assortativeness in Herpes Simplex Virus Type 1 Oral Transmission in the United States: A Mathematical Modeling Analysis.
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