Transcriptomic Profiling of Lesional and Perilesional Skin in Atopic Dermatitis Suggests Barrier Dysfunction, Inflammatory Activation, and Alterations to Vitamin D Metabolism.

In contrast, these associations were markedly attenuated in IL skin, where the correlations between CYP27B1 and the same genes were weaker or only partially significant: CTNNA1 (r = 0.76, p < 0.001), CDH1 (r = 0.30, p = 0.181), and TJP1 (r = 0.59, p = 0.005). 2.4.

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