Clinical Safety and Efficacy of Allogeneic Adipose Stem Cells: A Systematic Review of the Clinical Trials.

Int J Mol Sci · 2025 · PMC12249789 · PMID 40650153

Europe PMC DOI

hedged sentences

0.0530

closest p · 1.1× alpha

0.0530

boldest claim

The sentences

a trend towards significancep = 0.053so close (0.05 < p ≤ 0.1)

For secondary endpoints, at week 12, 82% of subjects in the treatment group achieved complete closure (18 of 22) versus 53% in the control group (9 of 17), with a trend towards significance ( p = 0.053).

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a positive trendno p-value reported

However, a positive trend was noted in NIHSS scores, with a median score of 3 (IQR: 3–6.75) in the AASCs group compared to 7 (IQR: 0–12.5) in the placebo group at 24 months.

also in 11,005 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.