Barely Significant
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Common SNCA Genetic Variants and Parkinson's Disease Risk: A Systematic Review and Meta-Analysis.

Int J Mol Sci · 2025 · PMC12250285 · PMID 40649779

Europe PMCDOI
3
hedged sentences
0.0446
closest p · 0.9× alpha
0.0446
boldest claim

The sentences

borderline significantp -value = 0.0446actually significant
C) included seven studies [ 9 , 19 , 20 , 25 , 26 , 27 ] and showed a borderline significant association with PD risk (OR = 1.22, 95% CI: 1.00–1.48, p -value = 0.0446; I 2 = 79.2%; Figure 3 A).

also in 11,409 other papers

marginally significantno p-value reported
A marginally significant effect was observed under the allelic model; however, this association lacked robustness due to substantial heterogeneity and inconsistent sensitivity analysis results.

also in 26,082 other papers

marginal significanceno p-value reported
In contrast, rs2583988 showed marginal significance in the allelic model, which was lost after sensitivity analyses.

also in 5,069 other papers

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