Androgen receptor promotes arachidonic acid metabolism and angiogenic microenvironment in AFP-negative hepatocellular carcinoma.

Nat Commun · 2025 · PMC12255818 · PMID 40651942

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Clinical information of these patients was provided in Supplementary Data 1 , with no significant differences in HBsAg, antiviral treatment, liver cirrhosis status, tumor number; modestly significant bias in gender, age and tumor size ( p < 0.05); and significantly lower microvascular invasion (MVI), Barcelona Clinic Liver Cancer (BCLC) stages and Edmondson-Steiner (E-S) grades in AFP − HCC versus AFP + HCC ( p < 0.001).

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