Overcoming immune resistance in advanced esophageal squamous cell carcinoma with recombinant human adenovirus type 5 by impacting the immune microenvironment: a case report.

Front Immunol · 2025 · PMC12256217 · PMID 40661951

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

an increasing trendno p-value reported

Between the two recurrences, there was an increasing trend in the infiltration of CD3, CD4, CD8, and CD20 immune cells in the tumor microenvironment after H101 injection, while PD-L1 and IFN-γ expression initially decreased and then increased, and IL-1β was consistently upregulated.

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.