highly significantp < 0.0001
The model also showed significant correlations with clinical markers, including faecal calprotectin ( r s = 0.50), C-reactive protein (CRP; r s = 0.45) and Physician Global Assessment ( r s = 0.45), all of which were highly significant ( p < 0.0001), supporting the clinical validity of UC-SCALE. 23 Aside of CNNs, other computational methods have been employed to detect mucosal inflammation.