Interleukin-17A signaling promotes CD8+ T cell cytotoxicity against West Nile virus infection through enhancing PI3K-mTOR-mediated metabolism.

PLoS Pathog · 2025 · PMC12258563 · PMID 40632810

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a slight trendno p-value reported

In addition, treatment with rIL-17A also increased the expression of S6K1 in CD8 + T cells from Il17a -/- mice, albeit the expression of PIK3ca and mTOR showed a slight trend of increase after the treatment, but the change was not statistically significant ( Fig 6B - D ).

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