In case of sIgG 4 , the fold increase ( t = 1 to t = 3) was highly significant for BPE‐AC (13.9‐fold increase for BPE and 20.8‐fold for Bet v 1), and at t = 3, both BPE‐ and Bet v 1‐sIgG 4 were significantly higher compared to placebo t = 3 (Figure 2D ).
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Subcutaneous Allergen Immunotherapy With Hypoallergenic Bet v 1 Compared to Conventional Extract: Poorer Blocking Antibody Capacity Dominated by IgG<sub>1</sub> Instead of IgG<sub>4</sub>.
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