Modulating immune cell fate and inflammation through CRISPR-mediated DNA methylation editing.

Sci Adv · 2025 · PMC12266127 · PMID 40668918

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a nonsignificant trendno p-value reported

While a nonsignificant trend toward increased total colony numbers was observed in sh IL1RN conditions, IL1RN-depleted CD34 + cells showed a marked reduction in the formation of mature myeloid colonies ( Fig. 4, H and I ).

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