Barely Significant
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Exercise-induced mitochondrial protection in skeletal muscle of ovariectomized mice: A myogenic E<sub>2</sub> synthesis-independent mechanism.

Redox Biol · 2025 · PMC12266561 · PMID 40578025

Europe PMCDOI
2
hedged sentences
0.0800
closest p · 1.6× alpha
0.0800
boldest claim

The sentences

trending toward significanceP=0.08so close (0.05 < p ≤ 0.1)
Furthermore, aromatase activity assays demonstrated a trend towards increased aromatase activity in the GAS muscle of OVX mice compared to the sham group ( P=0.08, trending toward significance ), and exercise training significantly increased aromatase activity in the GAS muscle of OVX mice ( Fig. 4 D).

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a decreasing trendno p-value reported
Exercise intervention showed a decreasing trend in MDA levels compared to OVX, but without statistical significance ( Fig. 3 E). 3.3.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.