At the Nexus Between Epigenetics and Senescence: The Effects of Senolytic (BI01) Administration on DNA Methylation Clock Age and the Methylome in Aged and Regenerated Skeletal Muscle.

Aging Cell · 2025 · PMC12266783 · PMID 40259517

Europe PMC DOI

hedged sentence

0.0890

closest p · 1.8× alpha

0.0890

boldest claim

The sentences

trending toward significancep = 0.089so close (0.05 < p ≤ 0.1)

In OV, BETA analysis was significant for upregulated genes after muscle regeneration ( p = 0.007, Figure 6B ) and was trending toward significance for downregulated genes ( p = 0.089, Figure 6B ).

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