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An integrin-based quercetin 7-rhamnoside liver-targeted delivery liposomes for intrahepatic cholestasis in pregnancy.

Mater Today Bio · 2025 · PMC12268842 · PMID 40677400

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a decreasing trendno p-value reported
Conversely, the expression of Sirtuin 1 (SIRT1), MFN2, peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α), FXR, CYP27A1, bile salt export pump (BSEP), and ABCB4 showed a decreasing trend in the vehicle-treated ICP model rat. t-QL significantly modulated the expression of genes towards that in normal animals.

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