Endothelial cell-secreted bone targeting exosomes promote angiogenesis coupling with osteogenesis via the PERK-ATF4-CRELD2 pathway.

Stem Cell Res Ther · 2025 · PMC12269303 · PMID 40671164

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highly significantno p-value reported

It was found that CRELD2 was highly significant in the HUVEC-Exos group than in the PBS group (Fig. 4 A).

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