a trend towards significancep = 0.055
This trend continued, with a trend towards significance in the second month (p = 0.055) and a statistically significant difference by the third month (14.0 vs. 9.5 days, p = 0.039).
This trend continued, with a trend towards significance in the second month (p = 0.055) and a statistically significant difference by the third month (14.0 vs. 9.5 days, p = 0.039).
However, there was a trend toward significance in headache frequency reduction during the first month, with the proximal group showing a median reduction of 11.0 attacks compared to 7.0 attacks for the distal group (p = 0.055) ( Table 3 , Figure 2 ) In terms of VAS score reductions, delta analysis ( Table 3 ) showed that the 3rd month change favored the Distal group (r = 0.325, p = 0.011), demonstrating a medium effect size.
Statistically highly significant reductions compared to baseline were observed in both groups for headache-related outcomes.