HMGB1 Exacerbates Intestinal Barrier Damage by Inducing Ferroptosis Through the TLR4/NF-κB/GPX4 Pathway in Ulcerative Colitis.

Mediators Inflamm · 2025 · PMC12274088 · PMID 40689397

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a decreasing trendno p-value reported

Our results showed that the expression levels of TLR4 and p-NF-κB in the colon tissues of mice in the DSS group were significantly increased, while the expression of GPX4 presented a decreasing trend.

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