The Vulpes vulpes montana genome provides insights into high-altitude adaptation mechanisms of the Vulpes species.

Commun Biol · 2025 · PMC12274459 · PMID 40681668

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However, under hypoxic conditions, the mRNA expression of IGSF22 S132F is not only substantially higher than that of the WT but also exhibits significant ( p < 0.05) and highly significant ( p < 0.01) differences compared to the expression levels of IGSF22 S132F and WT under normoxic conditions, respectively.

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