marginal significancep -value < 0.1
Substantial associations ( p -value < 0.05) with the eGFR slope were established for GPX3, FERMT3, CFHR1, and RARRES2, while marginal significance ( p -value < 0.1) was observed for SERPINF1, AFM, and elevated Mayo classes; conversely, age, sex, and eGFR did not retain statistical significance.